We carry out all relevant studies according to the most recent
and standardized guidelines (EPPO / OECD/ EPA). Apart from laboratory studies,
we equally offer tunnel and open field studies at various sites
throughout Europe and in Germany
 within our broad test site network.

Laboratory studies
• Determination of the LD 50 upon contact (OECD 214) or oral exposure (OECD 213)
• Determination of NOEC (LD 50) after chronic oral exposure
  (Decourty et al. (2005) / Suchail et al. (2001), BTC method no. 230)
• Determination of the LC 50 of larvae (OECD (Draft))

Semi-field studies
• Observation of mortality, flight density, brood development and the behaviour of bee colonies
   after the exposure of small colonies in tents and tunnels (OECD GC No. 75, EPPO PP 1/170(4)
• possible melliferous plants: Phacelia, rape seed, mustard, clover

Field studies
• Observation of mortality, flight density, development of colonies, brood development
  and the behavior of bee colonies after exposure under real conditions
  (EPPO PP 1/170(4), Oomen PA, De Ruijter A and Van der Steen J, EPPO 22: 613-616 (1992))
• possible melliferous plants: Phacelia, rape seed, mustard, apple

The documentation and evaluation of the brood development (Brood termination rate /Brood indices) is carried
out by means of computer-aided image processing (NEXTREAT‘s Bee Brood Analysis Package, 1.0 (2011)).